Technical: Eroded Subcortical White Matter mask
Published:
Blog posts
2024
2023
Paper on amyloid-first and tau-first heterogeneity (data-driven subtypes) in Alzheimer’s disease
Published:
Latest paper in the journal Brain is a wonderful piece of work led by the intrepid Leon Aksman, who analysed antemortem and postmortem data from the ADNI and ROSMAP cohorts to unravel some mysteries surrounding the interplay between two key pathologies in Alzheimer’s disease progression: amyloid and tau.
2021
New paper on data-driven progression subtypes in Alzheimer’s disease
Published:
Latest paper is an amazing collaboration led by the wonderful Jake Vogel that pulled together the largest database so far of tau PET imaging of Alzheimer’s pathology in the living brain, then unleashed Alex Young’s SuStaIn algorithm to discover four previously unknown/uncharacterised subtypes.
Vacancy: Research Assistant in Memory Clinic Image Computing
Published:
Apply Here (closing date: 23 May 2021)
2020
CompAge 2020
Published:
Here’s my poster: Model-based subtypes of disease progression in Parkinson’s
2018
UCL postdoc job
Published:
Want to work with me on computational modelling of neurological disease progression like Alzheimer’s, multiple sclerosis, and prion diseases?
Data-driven computational models of familial Alzheimer’s disease
Published:
[UPDATE] The published version is available here: Brain 141(5), awy050 (2018).
“The paper is a pleasure to read, as well as scientifically insightful.” — Journal Editor
2017
Sequential disconnection of the brain in Alzheimer’s disease
Published:
My latest paper on Alzheimer’s disease progression is available in Frontiers in Neurology:
Imaging plus X
Published:
My work in the EuroPOND consortium is neatly summarised in our latest paper, where we review the emerging field of data-driven disease progression modelling. It’s open access, so anyone can download and read it for free from here:
2016
Technical: MRtrix ACT using GIF parcellation
Published:
Software: MRtrix 3 (0.3.15) Pipeline: Anatomically Constrained Tractography (ACT)
Decoding Alzheimer’s and Parkinson’s disease
Published:
Following a press-release today (23 March 2016), Dr. Laura Phipps from Alzheimer’s Research UK wrote a blog post about my research into Alzheimer’s disease and Parkinson’s disease. Check it out: www.dementiablog.org/using-computers-to-decode-alzheimers
2014
Event-based model of Alzheimer’s disease
Published:
Our POND team at UCL have modelled the changes in Alzheimer’s disease, confirming our current understanding of this disease, and providing a tool for diagnosis and prognosis. You can read about it for free in the journal Brain here (open access). Title and abstract below.
2013
Ideal Gas Law works for soft crystals
Published:
Working with folk from my old stomping ground at the University of Liverpool, we discovered in the laboratory that a two-dimensional dusty plasma can be adequately described using the ideal gas law - even when shock waves are excited to melt the dust crystal.
2012
UCL
Published:
I have started my new role at University College London (UCL). I am working on computational models of neurodegenerative disease progression. Read more here.
APS March Meeting 2012
Published:
I will present some results on dusty plasmas at this year’s American Physical Society March Meeting in Boston, USA. My talk is scheduled for the High Pressure: Experiment session on Thursday March 1. I’ll be talking about combining Rankine-Hugoniot shock relations and target tracking to derive an equation of state for a dusty plasma.
2011
Tracking shocked dust
Published:
Our group’s latest paper has been accepted for publication published in Physics of Plasmas:
Quantum filtering one bit at a time
Published:
Update (2011-12-22): Our paper has now been published in Physical Review Letters here: 10.1103/PhysRevLett.107.260503.
Update (2011-11-11): Our paper has been accepted for publication in Physical Review Letters.
Garmisch
Published:
I recently visited Garmisch-Partenkirchen to participate in the 6th annual International Conference on the Physics of Dusty Plasmas. The conference was excellent. Full of very interesting talks and a decent social program, too. See photos below.
2010
New paper
Published:
Our group recently published a paper entitled “Molecular Dynamics Simulations of Dynamic Phenomena in Complex Plasmas” in IEEE Transactions on Plasma Science.
SPIE in Orlando
Published:
I’ll be presenting a talk in Orlando, Florida (U.S.A.) at the SPIE conference “Signal and Data Processing of Small Targets 2010” on Tuesday, 6 April (the final talk of the day). It’s in the Sensor Data and Information Exploitation program track of the “Defense, Security and Sensing” symposium.*