Published in Brain, 2018
Dominantly-inherited Alzheimer's disease is widely hoped to hold the key to developing interventions for sporadic late onset Alzheimer's disease. We use emerging techniques in generative data-driven disease progression modelling to characterize dominantly-inherited Alzheimer's disease progression with unprecedented resolution, and without relying upon familial estimates of years until symptom onset.
Recommended citation: N.P. Oxtoby, et al. (2018). "Data-driven models of dominantly-inherited Alzheimer's disease progression" Brain 141(5) https://doi.org/10.1093/brain/awy050