Neurodegenerative Disease Progression

My research focusses on developing and applying computer science approaches to determining the progression of degenerative neurological diseases like Alzheimer’s and Parkinson’s. I am a UKRI Future Leaders Fellow, and co-leader of the POND group in CMIC at UCL.

I’m the Scientific Manager (and Co-Investigator) for the EuroPOND consortium.

Funding sources:
  • UKRI Future Leaders Fellowship.
    “I AIM: Individualised Artificial Intelligence for Medicine”; Total £1M. Jan 2020 – Dec 2023.
  • Horizon 2020 (Co-I; PI Danny Alexander)
    EuroPOND: Data-driven models for progression of neurological diseases.”; Total: €5.5M (UCL €1.8M).
    Jan 2016 – Dec 2020.
  • EU JPND (via UK MRC) (Co-I; PI Danny Alexander)
    E-DADS: Early Detection of Alzheimer’s Disease Subtypes”; Total: €2M. 4 years.
Past Funding:

Soft crystal physics: Complex Plasmas

Some of my previous research at the University of Liverpool was in the area of dusty plasmas, which are essentially toy systems for exploring the physics of soft crystals. A dusty plasma is a mixture of neutral gas atoms, positive ions, electrons and micrometer-sized `dust’ particles (plastic spheres in our experiments). This work involved image processing (segmentation, registration, etc.), object tracking (dynamics modelling), and data analysis.

Quantum Filtering, et al.

Other interests include machine learning, quantum filtering, state estimation, and object tracking.

Publications are here.
Publications on complex plasmas are here.
Most of my early research results can be found on the arXiv. More recently I’ve been using bioRxiv.

Feel free to contact me for further information.

Collaborators, present and past

    Danny Alexander (UCL, UK); Alexandra Young (KCL, UK); et al.
    Nick Fox, Jon Schott, Rimona Weil, Antoinette O’Connor, Seb Crutch, et al.
Zuzana Walker (UCL Psychiatry)

Jason Ralph
(Liverpool, UK)
Mark Sullman (Cranfield, UK)
Jared Cole (RMIT, Melbourne, Australia)
Jay Gambetta (IBM Watson Research Centre, NY, USA)
Susana Huelga (Universität Ulm, Germany)
Ángel Rivas (Universidad Complutense de Madrid, Spain)
Howard Wiseman (Griffith University, Brisbane, Australia)